Phenylcarbamic acid esters
Medchemexpress LLC N-(Boc-PEG2)-N-bis(PEG3-azide) | 2353409-46-6 | >98% | C28H53N7O11 | 250 MG
N-(Boc-PEG2)-N-bis(PEG3-azide) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It acts as a versatile click chemistry reagent, containing an azide group that enables participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Features an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Appears as a colorless to light yellow viscous liquid
Medchemexpress LLC β-N-Acetylhexosaminidase, Streptococcus pneumoniae | 9012-33-3 | 10 U
β-N-Acetylhexosaminidase (EC 3.2.1.52) is an exoglycosidase that catalyzes the hydrolysis of terminal non-reducing β-N-acetylgalactosamine and glucosamine residues in oligosaccharides for epigenetic applications.
- Exoglycosidase enzyme
- Catalyzes hydrolysis of terminal non-reducing β-N-acetylgalactosamine and glucosamine residues
- Useful for epigenetic applications
Medchemexpress LLC N-Phenethylbenzamide | 3278-14-6 | 99.56% | 225.29 | 1 ML
N-Phenethylbenzamide is an active compound extracted from *Liriodendron tulipifera*. It is used for the research of inflammatory diseases.
- Active compound from natural source
- Suitable for inflammatory disease research
- High purity
Medchemexpress LLC N-Nitrosodiethylamine | 55-18-5 | 1 ML
N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. It is found in tobacco smoke, water, cheddar cheese, cured and fried meals, and many alcoholic beverages. This compound causes changes in nuclear enzymes related to DNA repair/replication and leads to various tumors in all animal species, primarily affecting the nasal cavity, trachea, lung, esophagus, and liver.
- Potent hepatocarcinogenic dialkylnitrosoamine.
- Found in various common consumables and environmental factors.
- Induces changes in nuclear enzymes related to DNA repair/replication.
- Causes various tumors in all animal species.
- Primarily affects specific organs including the nasal cavity, trachea, lung, esophagus, and liver.
- Can be utilized to establish hepatocellular carcinoma models.
Medchemexpress LLC Boc-N-Amido-PEG3-azide | 642091-68-7 | C13H26N4O5 | 250 MG
Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker employed in the synthesis of PROTACs. This click chemistry reagent features an azide group that enables participation in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. It contributes to the formation of PROTACs, which utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group for click chemistry reactions
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Colorless to light yellow liquid appearance
Medchemexpress LLC GSTM2 protein, human (N-His) | ≥98.0% | 50 UG
Recombinant full-length human Glutathione S-transferase Mu 2 (GSTM2) with an N-terminal 6xHis tag, expressed in E. coli and supplied lyophilized for research applications. Characterized for purity, activity, and low endotoxin to support biochemical and immunological assays.
- Recombinant full-length human protein with N-terminal 6xHis tag.
- Expressed in E. coli expression system.
- Lyophilized formulation with trehalose and Tween-80 for stability.
- Purity ≥98.0% by reducing SDS-PAGE.
- Bioactivity 10-15 U/mg (CDNB substrate assay).
- Endotoxin level <1 EU/μg.
- Not recommended to reconstitute below 100 μg/mL.
Medchemexpress LLC Ccr2 protein, mouse (N-His, C-Myc) | 93.0% | 100UG
Recombinant CCR2 protein (mouse) representing amino acids M1-A55, expressed in Escherichia coli and supplied with an N-terminal 10xHis tag and a C-terminal c-Myc tag. The preparation has an apparent molecular weight of ~16 kDa and purity greater than 90% by reducing SDS-PAGE. It is intended for in vitro biochemical and binding studies involving CCR2 and its ligands. Store lyophilized or frozen, and aliquot to avoid freeze-thaw.
- Recombinant fragment corresponding to CCR2 (mouse)
- N-terminal 10xHis and C-terminal c-Myc tags for detection and purification
- Expressed in Escherichia coli for high-yield production
- Approximate molecular weight 16 kDa
- Purity greater than 90% as determined by reducing SDS-PAGE
- Suitable for biochemical and binding assays
- Stable when stored at -20°C or -80°C; aliquot to avoid freeze-thaw
Medchemexpress LLC COMMD8 Human N-His 50ug | 50ug
COMMD8 Protein Human (N-His) expresses in E coli with a His tag at the N-terminus COMMD8 is a protein that binds to the C-terminal amino acid sequence (residues 306 352) of human CXCR4[1]
Medchemexpress LLC 10-((tert-butoxycarbonyl)amino)decanoic acid | 173606-50-3 | MFCD00270351 | >98.0% | 287.40 g·mol⁻¹ | C15H29NO4 | 25 G
Boc-10-aminodecanoic acid (10-((tert-butoxycarbonyl)amino)decanoic acid) is a Boc-protected amino acid used as a linker building block in peptide synthesis and PROTAC construction. It contains a terminal carboxylic acid and a Boc-protected amine that enable standard coupling reactions and selective deprotection.
- Boc-protected amino acid with terminal carboxylic acid.
- Suitable for peptide synthesis and PROTAC linker construction.
- High purity for research applications.
- Soluble in common organic solvents for coupling chemistry.
- Available in multiple pack sizes, including 25 g.
Medchemexpress LLC N-Nornuciferine | 4846-19-9 | 1 ML
N-Nornuciferine is an aporphine alkaloid derived from lotus leaf. It is known for its significant inhibitory activity against the CYP2D6 enzyme, with IC50 and Ki values of 3.76 μM and 2.34 μM, respectively.
- Derived from lotus leaf
- Selectively inhibits CYP2D6 activity
- Shows weak or no inhibition of other P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9)
- Competitively inhibits dextromethorphan o-demethylation
Medchemexpress LLC N-Boc-N-bis(PEG2-acid) | 2054339-01-2 | 99.9% | C19H35NO10 | 500 MG
N-Boc-N-bis(PEG2-acid) is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, making them suitable for research applications.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC N-Methylflindersine | 50333-13-6 | 1 MG
N-Methylflindersine is a compound isolated as insect antifeedants from the East African Rutaceous medicinal plants *Fagara chalybea* and *F. holtziana*. It is intended for research use only.
- High purity (99.91%)
- Isolated from natural sources
- Available with data sheet, COA, and SDS
- Antiinflammatory activity in human neutrophils
- White to off-white solid appearance
- Store at -20°C, sealed, away from moisture and light
Medchemexpress LLC PSME3 protein, human (N-His) | 5 UG
Recombinant human PSME3 (proteasome activator complex subunit 3) expressed in E. coli with an N-terminal His tag. Supplied as a lyophilized powder formulated in PBS with trehalose; suitable for biochemical assays and activity measurements.
- Approximately 33 kDa molecular weight.
- Lyophilized powder formulated in PBS, pH 7.4, with 8% trehalose.
- Endotoxin level <1 EU/μg (LAL method).
- Specific activity ~897.05 pmol/min/μg (suc-LLVY-AMC assay).
- Reconstitution recommended at ≥100 μg/mL in ddH2O.
- Store at -20°C; aliquot and freeze at -20°C or -80°C for long-term storage.